Neural tissue engineering is a new therapy that supports nerve repair and regeneration. In order to reconstruct the complex environment of neuronal development and maturation, a ideal neural tissue engineering biomaterials require many properties and capabilities, including proper biological and physical induction, as well as adsorption and release of specific growth factors. Chia-Chen Hsu of Imperial College London proposed the construction based on bovine serum albumin fiber electrospun scaffolds, which were doped with hemin to improve conductivity. And then combining recombinant proteins and growth factors to promote cell attachment and proliferation. The potential of combined morphology, biochemistry and electrical stimulation in neural tissue engineering applications has been demonstrated. Hemin-doped bovine serum albumin fiber scaffolds facilitate adhesion, proliferation and neuronal differentiation of human induced pluripotent stem cells (hiPSCs), and are able to bind and slowly release growth factors. It has a positive effect on neuronal maturation, and the neurons show more neurite outgrowth than controls by combined with electrical stimulation. The hemin-doped serum albumin fiber scaffold has wide application value in nerve regeneration engineering by promoting hiPSCs proliferation, differentiation and neurite branching.